Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): I. Psychosis superspectrum


Journal article


Roman Kotov, Katherine G Jonas, William T Carpenter, Michael N Dretsch, Nicholas R Eaton, Miriam K Forbes, Kelsie T Forbush, Kelsey Hobbs, Ulrich Reininghaus, Ulrich Reininghaus, Tim Slade, Susan C South, Matthew Sunderland, Monika A Waszczuk, Thomas A Widiger, Aidan G C Wright, David H Zald, Robert F Krueger, David Watson
World Psychiatry, vol. 19(2), 2020 May 1, pp. 151-172


DOI Wiley Online Library PubMed
Cite

Cite

APA   Click to copy
Kotov, R., Jonas, K. G., Carpenter, W. T., Dretsch, M. N., Eaton, N. R., Forbes, M. K., … Watson, D. (2020). Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): I. Psychosis superspectrum. World Psychiatry, 19(2), 151–172. https://doi.org/10.1002/wps.20730


Chicago/Turabian   Click to copy
Kotov, Roman, Katherine G Jonas, William T Carpenter, Michael N Dretsch, Nicholas R Eaton, Miriam K Forbes, Kelsie T Forbush, et al. “Validity and Utility of Hierarchical Taxonomy of Psychopathology (HiTOP): I. Psychosis Superspectrum.” World Psychiatry 19, no. 2 (May 1, 2020): 151–172.


MLA   Click to copy
Kotov, Roman, et al. “Validity and Utility of Hierarchical Taxonomy of Psychopathology (HiTOP): I. Psychosis Superspectrum.” World Psychiatry, vol. 19, no. 2, May 2020, pp. 151–72, doi:10.1002/wps.20730.


BibTeX   Click to copy

@article{roman2020a,
  title = {Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): I. Psychosis superspectrum},
  year = {2020},
  month = may,
  day = {1},
  issue = {2},
  journal = {World Psychiatry},
  pages = {151-172},
  volume = {19},
  doi = {10.1002/wps.20730},
  author = {Kotov, Roman and Jonas, Katherine G and Carpenter, William T and Dretsch, Michael N and Eaton, Nicholas R and Forbes, Miriam K and Forbush, Kelsie T and Hobbs, Kelsey and Reininghaus, Ulrich and Reininghaus, Ulrich and Slade, Tim and South, Susan C and Sunderland, Matthew and Waszczuk, Monika A and Widiger, Thomas A and Wright, Aidan G C and Zald, David H and Krueger, Robert F and Watson, David},
  month_numeric = {5}
}

Abstract

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary boundaries between psychopathology and normality, frequent disorder co-occurrence, heterogeneity within disorders, and diagnostic instability. This paper synthesizes evidence on the validity and utility of the thought disorder and detachment spectra of HiTOP. These spectra are composed of symptoms and maladaptive traits currently subsumed within schizophrenia, other psychotic disorders, and schizotypal, paranoid and schizoid personality disorders. Thought disorder ranges from normal reality testing, to maladaptive trait psychoticism, to hallucinations and delusions. Detachment ranges from introversion, to maladaptive detachment, to blunted affect and avolition. Extensive evidence supports the validity of thought disorder and detachment spectra, as each spectrum reflects common genetics, environmental risk factors, childhood antecedents, cognitive abnormalities, neural alterations, biomarkers, and treatment response. Some of these characteristics are specific to one spectrum and others are shared, suggesting the existence of an overarching psychosis superspectrum. Further research is needed to extend this model, such as clarifying whether mania and dissociation belong to thought disorder, and explicating processes that drive development of the spectra and their subdimensions. Compared to traditional diagnoses, the thought disorder and detachment spectra demonstrated substantially improved utility: greater reliability, larger explanatory and predictive power, and higher acceptability to clinicians. Validated measures are available to implement the system in practice. The more informative, reliable and valid characterization of psychosis-related psychopathology offered by HiTOP can make diagnosis more useful for research and clinical care.


Share



Follow this website


You need to create an Owlstown account to follow this website.


Sign up

Already an Owlstown member?

Log in